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Felicia MIHAI

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Articole semnate de acelasi autor in Revista Practica Medicala:

Femoral bone relapse in adult acute lymphoblastic leukemia Philadelphia chromosome positive: a case report

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Romanian Journal of Medical Practice | Vol. IX, No. 4 (37), 2014
ISSN 1842-8258  |  e-ISSN 2069-6108
ISSN-L 1842-8258
DOI: 10.37897/RJMP

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National Awards “Science and Research”

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Promoting Global Health

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Femoral bone relapse in adult acute lymphoblastic leukemia Philadelphia chromosome positive: a case report

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ABSTRACT

We present a case of a 39-year-old male patient diagnosed with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who relapse in unusual extramedullary site like bone. The patient was admitted complaining of intense pain in the left thigh 1 year following complete remission. Magnetic resonance imaging (MRI) revealed abnormal multifocal involvement in the left femur suggested malignancy. Bone marrow aspiration indicated recurrence of leukemic cells. These findings suggested bone relapse occurred simultaneously with medullary relapse.

Keywords: acute lymphoblastic leukemia, Philadelphia chromosome, bone relapse

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Particularitati de management al unui caz de purpura trombocitopenica imuna supraacuta în sarcina, finalizat cu splenectomie

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Romanian Journal of Medical Practice | Vol. X, No. 1 (38), 2015
ISSN 1842-8258  |  e-ISSN 2069-6108
ISSN-L 1842-8258
DOI: 10.37897/RJMP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJMP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

Particularitati de management al unui caz de purpura trombocitopenica imuna supraacuta în sarcina, finalizat cu splenectomie

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REZUMAT

Splenectomia este o manevră terapeutică cu indicaţie pentru o mare listă de afecţiuni, în principal hematologice. Dintre acestea, putem enumera anomaliile liniei eritrocitare: anemia hemolitică, sferocitoza ereditară sau talasemia, care au indicaţie de splenectomie în urma eşecului tratamentului medicamentos. O varietate de afecţiuni trombocitopenice sunt îmbunătăţite în urma splenectomiei, cea mai frecventă indicaţie fiind purpura trombocitopenică imună (PTI). Splenectomia la aceste grupe de pacienţi comportă un risc de infecţii fulminante, letale, care pot fi evitate cu tratamentul profilactic corespunzător. Cu toate că splenectomia în PTI nu are rol curativ, neîndepărtând sursa injuriei autoimune, aceasta conduce la îmbunătăţirea simptomelor, îmbunătăţirea valorilor trombocitelor, cu lipsa necesităţii unui tratament imunosupresor ulterior şi îmbunătăţirea calităţii vieţii.

Cuvinte cheie: splenectomie, splenectomie laparoscopică, purpură trombocitopenică imună, PTI, purpură trombocitopenică imună în sarcină

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