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Therapeutic strategies in primary malignancies of the vagina – a literature review
Nicolae BACALBASA, Olivia IONESCU and Irina BALESCU
ABSTRACT
Primary vaginal cancers are very rare malignancies accounting for only 1 to 2% of all gynecologic malignancies. The most frequent histologic subtype is squamous cell carcinoma followed by adenocarcinoma. Due to its rarity, data concerning the natural history, prognostic factors, and treatment are rather poor; however an extension of the reported clinical experience for cervical and anal cancer has been proposed given the similarities in disease etiology and the desire for organ preservation. This is a literature review of the most appropriate therapeutic strategies used in vaginal cancer management.
Keywords: vaginal cancer, squamous cell carcinoma, radiation therapy